USE OF A HIGH PLATELET-TO-RBC RATIO OF 2:1 IS MORE EFFECTIVE IN CORRECTING TRAUMA-INDUCED COAGULOPATHY THAN A RATIO OF 1:1 IN A RAT MULTIPLE TRAUMA TRANSFUSION MODEL

Abstract Background Platelet dysfunction importantly contributes to trauma-induced coagulopathy (TIC).Our aim was to examine the impact of transfusing platelets (PLTs) in a 2:1 PLT-to-red blood cell (RBC) ratio versus the standard 1:1 ratio on transfusion requirements, correction of TIC, and organ damage in a rat multiple trauma transfusion model.M

Considering the complexity of hydrological processes, it seems that multivariate methods may enhance the accuracy of time series models and the results obtained from them by taking more influential factors into account.Indeed, the results of multivariate models can improve the results of description, modeling, WOMENS HIGH HEELS and prediction of di

ABSTRACT Background Germline mutations in BRCA1/2 are known to cause hereditary tumors in the breast, ovary, and other organs.With the widespread adoption of comprehensive diagnostics, including comprehensive genomic profiling (CGP) tests for solid tumors, many patients with BRCA1/2 variants have been identified.Methods In this study, we extracted